BriefCase - Coronary Artery Calcification (CAC) Quantification

Aidoc
Aidoc's coronary artery calcification algorithm is a quantification algorithm that opportunistically runs on non-gated, non-contrast CTs to provide radiologists with a measurement of the levels of calcified plaques within coronary arteries.
Information source: Vendor
Last updated: February 16, 2025

General Information

General
Product name BriefCase - Coronary Artery Calcification (CAC) Quantification
Company Aidoc
Subspeciality Cardiac
Modality CT
Disease targeted Coronary artery calcification
Key-features Coronary Artery Calcification (CAC) scoring
Suggested use During: perception aid (prompting all abnormalities/results/heatmaps),
During: report suggestion

Technical Specifications

Data characteristics
Population Adult patients aged 30 and older
Input Non-cardiacgated non-contrast CT (NCCT) images that include the heart
Input format DICOM
Output 4 levels based upon the calculated total Agatston score: Very Low (0), low (1-100), medium (101-400) and high (>400). DICOM series with calcification indicated on images.
Output format Annotated images: DICOM Secondary Capture as a new DICOM series Report output: DICOM Structured Report
Technology
Integration Integration in standard reading environment (PACS)
Deployment Hybrid solution, Cloud based, Locally on dedicated hardware
Trigger for analysis Automatically, right after the image acquisition
Processing time

Regulatory

Certification
CE
Certified, Class IIa , MDR
FDA 510(k) cleared , Class II
Intended Use Statements
Intended use (according to CE) BriefCase-Quantification is a software intended for use in the analysis of non-cardiacgated non-contrast CT (NCCT) images that include the heart in adult patients aged 30 and older. The device is intended to assist physicians by providing the user with a fourcategory Coronary Artery Calcification (CAC) of plaques, which present a risk for coronary artery disease, together with preview axial images of the detected calcium meant for informational purposes only.

Market

Market presence
On market since 11-2023
Distribution channels Change Healthcare, Merge Merative
Countries present (clinical, non-research use)
Paying clinical customers (institutes)
Research/test users (institutes)
Pricing
Pricing model Subscription
Based on Number of analyses

Evidence

Evidence
Peer reviewed papers on performance
Non-peer reviewed papers on performance
Other relevant papers