BriefCase - Midline Shift (MLS) Quantification

Aidoc

Aidoc's midline shift algorithm is a quantification algorithm that automatically measures the farthest distance between the midline and the septum pellucidum of the brain. If the septum pellucidum is not aligned with the midline, it may indicate a midline shift which is a condition often associated with brain abnormalities.

Information source: Vendor
Last updated: February 16, 2025

General Information

General
Product name	BriefCase - Midline Shift (MLS) Quantification
Company	Aidoc
Subspeciality	Neuro
Modality	CT
Disease targeted	Midline shift
Key-features	Midline shift measurement
Suggested use	During: perception aid (prompting all abnormalities/results/heatmaps)

Technical Specifications

Data characteristics
Population	Adults or transitional adolescents aged 18 years and older
Input	Head CT without contrast
Input format	DICOM
Output	Preview image of the slice with the largest midline shift, measurement of the largest shift of the midline, table and a graph showing the measured midline shift over time
Output format	Annotated images: DICOM Secondary Capture as a new DICOM series Report output: DICOM Structured Report
Technology
Integration	Integration in standard reading environment (PACS)
Deployment	Hybrid solution, Cloud based, Locally on dedicated hardware
Trigger for analysis	Automatically, right after the image acquisition
Processing time

Regulatory

Certification
CE	Certified, Class IIa , MDR
FDA	510(k) cleared , Class II
Intended Use Statements
Intended use (according to CE)	The device is intended to assist appropriately trained medical specialists by providing the user with an automated current manual process of measuring midline shift. The device provides midline shift measurement from NCCT images acquired at a single time point, and can additionally provide an output with comparative analysis of two or more images that were acquired in the same individual at multiple time points.

Market

Market presence
On market since	11-2023
Distribution channels	Change Healthcare, Merge Merative
Countries present (clinical, non-research use)
Paying clinical customers (institutes)
Research/test users (institutes)
Pricing
Pricing model	Subscription
Based on	Number of analyses

Evidence

Evidence
Peer reviewed papers on performance
Non-peer reviewed papers on performance
Other relevant papers