BriefCase - Midline Shift (MLS) Quantification

Aidoc
Aidoc's midline shift algorithm is a quantification algorithm that automatically measures the farthest distance between the midline and the septum pellucidum of the brain. If the septum pellucidum is not aligned with the midline, it may indicate a midline shift which is a condition often associated with brain abnormalities.
Information source: Vendor
Last updated: February 16, 2025

General Information

General
Product name BriefCase - Midline Shift (MLS) Quantification
Company Aidoc
Subspeciality Neuro
Modality CT
Disease targeted Midline shift
Key-features Midline shift measurement
Suggested use During: perception aid (prompting all abnormalities/results/heatmaps)

Technical Specifications

Data characteristics
Population Adults or transitional adolescents aged 18 years and older
Input Head CT without contrast
Input format DICOM
Output Preview image of the slice with the largest midline shift, measurement of the largest shift of the midline, table and a graph showing the measured midline shift over time
Output format Annotated images: DICOM Secondary Capture as a new DICOM series Report output: DICOM Structured Report
Technology
Integration Integration in standard reading environment (PACS)
Deployment Hybrid solution, Cloud based, Locally on dedicated hardware
Trigger for analysis Automatically, right after the image acquisition
Processing time

Regulatory

Certification
CE
Certified, Class IIa , MDR
FDA 510(k) cleared , Class II
Intended Use Statements
Intended use (according to CE) The device is intended to assist appropriately trained medical specialists by providing the user with an automated current manual process of measuring midline shift. The device provides midline shift measurement from NCCT images acquired at a single time point, and can additionally provide an output with comparative analysis of two or more images that were acquired in the same individual at multiple time points.

Market

Market presence
On market since 11-2023
Distribution channels Change Healthcare, Merge Merative
Countries present (clinical, non-research use)
Paying clinical customers (institutes)
Research/test users (institutes)
Pricing
Pricing model Subscription
Based on Number of analyses

Evidence

Evidence
Peer reviewed papers on performance
Non-peer reviewed papers on performance
Other relevant papers