Saige Brain (Quantib® ND)

Saige Brain (previously Quantib® ND) offers automated segmentation of brain structures and white matter hyperintensities. This machine learning radiology application provides insight into the possible presence of atrophy related to Alzheimer’s disease or other types of dementia. Saige Brain's follow-up feature allows for tracking of neuro degeneration over time. Automatic assessment of white matter hyperintensity development supports monitoring of MS patients.The software distinguishes between new and previously identified WMHs, providing a visualization with color-coded lesions super positioned on an anatomical map.
Information source: Vendor
Last updated: Nov. 30, 2023

General Information

Product name Saige Brain (Quantib® ND)
Company DeepHealth
Subspeciality Neuro
Modality MR
Disease targeted Neurodegenerative disease, dementia, Alzheimer’s disease, multiple sclerosis
Key-features Brain structure segmentation and volume quantification, multiple time-point analysis, white matter hyperintensity detection and quantification, comparison to reference population
Suggested use During: interactive decision support (shows abnormalities/results only on demand), report suggestion

Technical Specifications

Data characteristics
Population All with suspicion of neuro degenerative disease, dementia, Alzheimer’s disease, MS
Input (contrast) 3DT1 MRI, (contrast) 3D or 2D T2 FLAIR MRI
Input format DICOM
Output segmentation overlays, draft radiology report including normative comparison
Output format DICOM
Integration Integration via AI marketplace or distribution platform, Stand-alone third party application
Deployment Locally on dedicated hardware
Trigger for analysis Automatically, right after the image acquisition, On demand, triggered by a user through e.g. a button click, image upload, etc.
Processing time > 10 minutes


Certified, Class IIa , MDR
FDA 510(k) cleared , Class II
Intended Use Statements
Intended use (according to CE) Quantib ND is a non-invasive medical imaging processing application that is intended for automatic labeling, visualization, and volumetric quantification of segmentable brain structures from a set of magnetic resonance (MR) images. The Quantib ND output consists of segmentations, visualizations and volumetric measurements of brain structures and white matter hyperintensities. Volumetric measurements may be compared to reference centile data. It is intended to provide the trained medical professional with complementary information for the evaluation and assessment of MR brain images and to aid the trained medical professional in quantitative reporting.


Market presence
On market since 09-2017
Distribution channels Nuance PIN
Countries present (clinical, non-research use)
Paying clinical customers (institutes)
Research/test users (institutes)
Pricing model Subscription
Based on Number of users, Number of installations


Peer reviewed papers on performance

  • Combining semi-quantitative rating and automated brain volumetry in MRI evaluation of patients with probable behavioural variant of fronto-temporal dementia: an added value for clinical practise? (read)

  • Comparing two artificial intelligence software packages for normative brain volumetry in memory clinic imaging (read)

Non-peer reviewed papers on performance
Other relevant papers