Liver Fat & Iron Concentration

Quibim has developed a virtual liver biopsy app that runs an automatic analysis of abdominal MR examinations containing a multi-echo chemical shift (MECSE) sequence with the help of AI. The solution provides a simultaneous quantification of fat and iron concentration with a single-peak approach. The output of the suite includes the parametric maps of fat and iron with voxelwise resolution and a quantitative structured report comparing the liver values of these imaging biomarkers to normative data. This tool supports the early detection, diagnosis, treatment response evaluation and follow-up of a wide range of liver diseases.
Information source: Vendor
Last updated: Nov. 19, 2021

General Information

Product name Liver Fat & Iron Concentration
Company Quibim
Subspeciality Abdomen
Modality MR
Disease targeted Diffuse liver diseases, Cirrhosis, Fibrosis, Steatohepatitis, Hemochromatosis, Metabolic syndrome, Obesity, Inflammatory activity
Key-features Liver segmentation, Quantification of PDFF and R2*
Suggested use Without interference of a radiologist: AI-only diagnosis

Technical Specifications

Data characteristics
Population Screening population
Input MRI MECSE Multi-Echo Chemical Shift Encoded
Input format
Output One-page structured report: PDFF and iron concentration parametric map, distribution table, statistics summary, steatosis grade
Output format DICOM Secondary Capture / PDF
Integration Integration in standard reading environment (PACS), Integration via AI marketplace or distribution platform, Stand-alone third party application, Stand-alone webbased
Deployment Locally on dedicated hardware, Locally virtualized (virtual machine, docker), Cloud-based, Hybrid solution
Trigger for analysis Automatically, right after the image acquisition
Processing time 1 - 10 minutes


Certified, Class IIa , MDD
FDA No or not yet
Intended Use Statements
Intended use (according to CE) Quibim Precision® is an image processing software package to be used by trained professionals including but not limited to physicians and medical technicians. The software runs in the browser of a standard “off-the-shelf” computer and can be used to perform image viewing, processing, and analysis of medical images. Data and images are acquired through DICOM compliant imaging devices and modalities.


Market presence
On market since 01-2019
Distribution channels
Countries present (clinical, non-research use) 4
Paying clinical customers (institutes) 5+
Research/test users (institutes) <5
Pricing model License
Based on Number of installations, Number of analyses


Peer reviewed papers on performance
Non-peer reviewed papers on performance
Other relevant papers França, M., Martí-Bonmatí, L., Porto, G., Silva, S., Guimaräes, S. and Alberich-Bayarri, Á. (2017). Tissue iron quantification in chronic liver diseases using MRI shows a relationship between iron accumulation in liver, spleen, and bone marrow. Clinical Radiology.

França, M., Alberich-Bayarri, Á. and Martí-Bonmatí, L. (2017). Accurate simultaneous quantification of liver steatosis and iron overload in diffuse liver diseases with MRI. Abdominal Radiology, 42(5), pp. 1434-1443.

Martí-Bonmatí, L., Alberich-Bayarri, Á. and Sánchez-González, J. (2012). Overload hepatitides: quanti-qualitative analysis. Abdom. Imaging. 37(2): 180-7.

Erturk, SM., Alberich-Bayarri, Á., Herrmann, KA., Martí-Bonmatí, L. and Ros, PR. (2009). Use of 3.0-T MR imaging for evaluation of the abdomen. Radiographics. 29(6): 1547-63.